Full Name
Zhvania Mzia (Ia)
Address
0162 Tbilisi, I. Chvachavadze av. 75, ap. 7
Phone
995 32 227 151 (home); 995 32 370 342 office)
Fax
995 32 941 045
E-mail
Web Page
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Date Of Birth
1950-09-25
Education
1996 - Doctor of Biological Science, Georgian State University 1980 - Candidate of Biological Science, Georgian Medical University 1974- 1978 - Post-graduate courses. Institute of Brain, Medical Academy of Science, Moscow 1968-1973 Georgian Institute of Foreign Languages, Faculty of French Language 1967-1972 - Biological faculty, Georgian State University
Position
Head, Laboratory of Brain Structure and Development, Georgian I. Beritashvili Institute for Physiology
Publications
Some articles (last 10 years): 1. Bolkvadze T., Japaridze N.D, Zhvania M.G., Kotaria N.T., Cicishvili A.Sh. Cellular composition of the piriform cortex of the rat brain in experimental epilepsy. Neurosci Behav Physiol. (New York) 2006 Mar; 36(3):271-4. 2. Kotaria N.T., Bolkvadze T., Zhvania M.G., Chkhikhvisvili C.L., Kiladze M., Melia N. Cell loss in different region of pirifirm cortex of rat at different time-points after status epilepticus induced by intraperitoneal injection of kainic acid. Georgian Journal of Neurosciences. 2006, 1, 5, 53-57. 3. Kotaria N.T., Bolkvadze T., Chkhikhvisvili C.L., Kiladze M., Melia N., Zhvania M.G. Quantitative analysis of cells in rat hippocampus at different time-points after status epilepticus induced by kainic acid administration. Georgian Journal of Neurosciences. 2006, 1, 5, 47-52 4. Bolkvadse T., Japaridze N.D, Zhvania M.G., Kotaria N.T., Cicishvili A.Sh. [Cellular composition of the rat piriform cortex in experimental epilepsy] Morfologiia (Sanct-Petersburg) 2005; 127(1): 14-7. Russian. 5. M. Zhvania, L.Lazrishvili. Discovery of new cellular structure - Porosome. Citologia (Moscow), 2005, 1. 6. Zhvania M.G., Bolkvadze T.A., Japaridze N.D. Solomonia R.O. Kuchiashvili N. Effect of kindling on GABA-ergic neurons of the hippocampus and pyriform cortex. Bull. Exp. Biol. Med. (Russia and USA). 2005 Jul; 140(1):48-50. 7. Zhvania M.G., Japaridze N.J., Bolkvadze T.A. Characteristics of structural organization of interneuronsin CA3 region and mossy fibers of hippocampus.Morfologiia. 2005; 127 (1): 78-83. Russian. 8. Ochigava I., Kalandarishvili L., Zhvania M. Immunological and neuromorphological study of Staphyloccocus aureus infected mice. 2005, 3, 1, 71-77. 9. Won Jin Cho, Aleksander Jeremic, K. Rognlien, Mzia Zhvania, Ilia lazrishvili, Bikashvili Tamar, Bhanu jena. Strusture, isolation, composition and reconstitution of the neuronal fusion pore. Cell Biology International, 2004, 28, 699-0708. 10. R. Solomonia, N.Kuchiashvili, A. Berulava, V. Pkhakadze, N.Trapaidze, M. Zhvania, T. Abesadze, H. Kojima, N. Dalakishvili. Purification and identification of the Aquilegia vulgaris extract fraction exhibiting anti-epilpetic activities. Journal of Biological Physics and Chemistry, 2004, 185-192. 11. Zhvania M. Discovery of the Molecular mechanism of Cellular Secretion. Journal of Biological Physics and Chemistry. 2004, 1 12. Japaridze N., Bolkvadze T.A., Zhvania M.G., Kotaria N., Cicishvili A. Influence of audiogenic stimulus on the cellular content in hippocampus of the Kroushinski-Molodkina rats. Proceedings of the Georgian Academy of Science, Biol. Ser. A, 2004 №6.vol.30, n.6, pp.925-928. 13. Bolqvadze T., Zhvania M.G., Japaridze N. The Influence of kindling on GABA-ergic neurons in hippocampus and piriform cortex. Proc. Georgian Academy of Science, Biol. Ser., A, 2004, 30. 6, 757-761. 14. M.G. Zhvania, N.A. Kostenko, "Structure of higher sections of the motor system of the rat brain after hypokinetic stress. J. Neurosci.and Behav. Physiol. (New York) 26, 3, (1998). 15. M.G. Zhvania. The influence of hypokinesia on the ultrastructure of rat neocortex. 1999. Bulletin of Experimental Biology and Medicine. Moscow. 125. 279-291. 16. М.Г. Жвания. Effect of hypokinetic stress on the ultrastructure of the rat neocortex, J. Bull. of Exp. Biol. and Med.. 125, 3, (1998). (journal is published in Russia and USA). 17. M.G. Zhvania. The Influence of hypokinesia on synapsoarchitectonics of rat limbic and extrapyramidal structures. Neurochemistry, Section 16. Other Clinical Aspects, Plenum-Press, New York. 1997. 18. М. G. Zhvania, Kostenko N.A. The influence of different forms of hypokinesia on the structure of motor regions of rat brain. Morfologyia,. 1997. 111, 1, 25-32 . 19. M.G. Zhvania. Synapsoarchitectonical changes in telencephalon of rat after influence of different forms of hypokinesia. J. Movement Disorders. London. 1997. 2312. S 1. 90-91 20. M.G. Zhvania. The Influence of hypokinesia on synapsoarchitectonical features of rat limbic and extrapyramidal structures, in Neurochemistry, Section 16. Other Clinical Aspects, Plenum-Press, New York. 1997. 21. М. Г. Жвания, Костенко Н.А. Влияние разных форм гипокинезии на структуру высших моторных отделов коры крысы. Морфология. 1997. 111, 1, 25-32 . 22. M.G. Zhvania. Synapsoarchitectonical changes in telencephalon of rat after influence of different forms of hypokinesia. J. Movement Disorders. London. 1997. 2312.S1.90-91 23. M.G. Zhvania, and I.M. Kakabadze, Ultrastructure of telencephalic mielinated fibers of the hypokinetic rat, Neurosci. and Behav. Physiol. (New York) 1996, 26, 3, 201-206.. 24. M.G. Zhvania, and N.A. Kostenko, The structure of the motor cortex of the brain of the hypokinetic rat," Neurosci. and Behav. Physiol. (New York) 1996. 26, 3,237-240. 13. 25. М.Г. Жвания. Ультраструктурная реорганизация лимбических отделов мозга крысы после воздействия уменьшенной двигательной активности, не вызывающей стресс. Морфология. Санкт-Петербург.1996. 109, 3. 10-14.\r\n26. Жвания М.Г. Реорганизация синапсоархитектоники конечного мозга крысы под воздействикм гипокинезии (количественное эктронномикроскопическое исследование). 1999. Бюлетень Экспериментальной Медицины и Биологии. Accepted for printing: Zhvania I.G, Bolkvadze T.A, Japaridze N.J., Kotaria N.T., Chkhikhvisvili C.L. The Influence of audiogenic stimulus on the number of cells of audiogenic structures in the Kroushinski-Molodkina rats. Experimental Biology and Medicine (Sanct Petersburg) Zhvania I.G, Bolkvadze T.A, Solomonia R.O., Japaridze N.J., Chkhartishvili B.G. The Influence of Auditory Stimulus on The Number of Cells of Limbic And Auditory Structures in The Kroushinski-Molodkina Rats. Zh Vyssh Nerv Deiat Im I P Pavlova. (Sanct-Petersburg). Bolkvadze T.A., Japaridze N.J., Zhvania M.G., Bikashvili T. Chilachava L. - The Hippocampal Cell Loss as a Result of Kindling; Morfologiia. (Russia). Solomonia R.O., Nozadze M., Kuchiashvili N., Bolkvadze T., Kiladze M., Zhvania M.G., Pkhakadze V., Kiguradze T. The Influence of Mio-Inozitol on the seizures provoked by pentiletetrazol and Kainic acid in rats. Exeprimental Biology and Medicine (Russian).
Conferences,contacts,other scientific and educational activities
Participation in scientific conferences, symposiums, congresses ( last 10 years). All materials were published 1. FENS (Federation of European Neuroscience) Congress. Vienna. Austria, 2006, June ? Presenter 2. SENCER (Science Education for New Civic Engagement and Responsibility). Santa Clara, California, USA. 2005, August ? Presenter 3. SENCER (Science Education for New Civic Engagement and Responsibility). Santa Clara, California, USA. 2004, August ? Presenter 4. IBRO/CEERC Summer School: "Research strategies for the study of complex neural networks: From synaptic transmission to seeing the brain in action?. Debrecen, Hungary, July, 2005, Co-Presenter of two reports (1. The Influence of Audiogenic Stimulus on the Number of Cells of Hippocampus in the Rats of Kroushinski-Molodkina Line? and 2. The Influence of Experimental Epilepsy on the Cells of Rat Piriform Cortex?). 5. 4th Forum of European Neuroscience. Lisbon, Portugal, July 2004 ? Presenter (?The immunohistochemical investigation of GABAergic neurons in hippocampal formation of rat brain after different forms of Temporal lobe epilepsy?). 6. International Symposium: Physiology of Yests and Filamentous Fungi. March, 2004, Anglet, France. Co-Presenter (Interactions between Saccaromyces genus yests and pathogenic bacteria) 7. European Congress in Microbiology. Tailand, February 2005 ? Co-Presenter 8. Annual Meeting of Sigma Xi (American Scientists Society) ? Galveston, Texas, USA. November 2002 ? Presenter 9. The Neurostereology Workshop ? Paris, France, July2002 - Participant 10. International Conference of Neurohystologists ?Kolosov?s Readings? ? Sanct-Petersburg, Russia, June, 2002 ? Presenter 11. European Symposium ?Glial Cell Function in Health and Disease?. Roma, Italy, June 2002 ? Presenter 12. Russian 27th Conference for Electron Microscopy. Russian Academy of Science. Chernogolovka, Russia, June, 1998 ? Presenter 13. European Symposium ?Glial Cell Function in Health and Disease?. Athens, Greece, June 1998 ? Presenter 14. American International Symposium for Neurochemistry. Boston, USA, September, 1997 ? Presenter 15. International Symposium ?Brain and Movemenet? ? Moscow-St.Petersburg, July, 1997 ? Presenter 16. European Symposium for Neurochemistry ? Gronningen, Netherlands, Avril, 1997 ? Presenter 17. 12th International Symposium ?Parcinson Disease? ? London, England, March, 1997 Presenter Also 5 presentations in local (Georgian) conferences. All materials were published. Contacts: Systematical contacts, discussions, collaboration with professors of Neuroscience and other specialty also directors of Teaching and Learning Centers from Iowa State University, Santa Clara University (California), George mason University (Virginia), Harrisburg University (Pensilavania), Brown University (USA), Wayne University (Michigan), Kuopio University (Finland), Helsinki University (Finland) and oth. As president of Sigma-Xi-Georgia (First International Partner of Sigma-Xi - Scietific Research Society, USA)and one three international coordinators of SENCER Program (Science Education for New Civic Engagement and Responsibility), funded by National Science Foundation, (USA)- has systematical email and mail communications with scientists from different universities of America Some Educational activities: 2003, June. International Conference ?Gaining Knowledge and Skills Needed for Scientific Communication and Collaboration?. Initiator and co-organizer (Principal organizer from Georgian side); 200 Conference was financed by American Research Society, Sigma Xi, American Academy of Science, UNESCO, CRDF, GRDF, INASP (England) and other international organizations. 2002, October. Sigma Xi- da Paccard Initiative for Creation Georgian Scientists Information Network. Autor of project and Person in charge.- 2003, March. Initiator and organizer of Sigma-Xi-Georgia (Sigma-Xi First International Partner) (Sigma-Xi ? American Scientific Research Society). President.- 2003, June ? SENCER- Program. Joint Seminar of American and Georgian Scientists. New Approaches for Science Education. Co-organizer. 2004, June ? SENCER- Program. Joint Seminar of American and Georgian Scientists. New Approaches for Science Education. Co-organizer 2005, June ? SENCER- Program. Joint Seminar of American and Georgian Scientists. New Approaches for Science Education. Co-organizer- 2005, June ? Organization of American bachelors? students visit. Iowa State University. During three weeks students performed research in Georgian Medical, Technical and State universities. One of the initiators and co-organizer. 2005, June. Organization of SENCER- American-Georgian Seminar: New Approaches for Science Education for New Civic Engagement and Responsibility. Tbilisi. Co-organizer 2005, June. Organization of SENCER- American-Georgian-Armenian Seminar: New Approaches for Science Education for New Civic Engagement and Responsibility. Co-organizer. Yerevan. Armenia. 2005, October - SENCER- Regional seminar: New Approaches in Science Education. Organizer. Batumi., Georgia 2005 ? Coordinator of 2 courses and 2 text-book preparation in Georgian Medical University (?AIDS/HIV? and ?Some Steps Away from Death?). Course and text-books preparation was finacned by SENCER-Program.- 2005, November. Certificate of Sigma-Xi Chapter Program Award (for International efforts for brain initiative to achieve public awareness about progress, promise and benefit of brain research. (a sPresident of Sigma-Xi-Georgia). Initiator and Organizer (with two Georgian scietists) of the visit of 8 American distingished professors (for distingished lectures). Some of them: 2003, June - Lloyd Anderson. Neuroscientist. Iowa State University (Neuroscientist); 2004, Novemeber -Bhanu Jena. Nanobiologist.Wayne State University, Detroit, Michigan, 2005, June ? David Tack. Neuroscientist. Santa Clara University, California. 2005, June, Michel Alar. Neuroanatomist. Harrisburg University, Pensilvania. 2005, Novemeber ? Gretchen Kalonji.Head of Department of Strategy for International Development. California State University. San Francisko. 2006, March ? Stive Freeman. Head of Teaching and Learning Center. Iowa State University.\r\n 2002, June,Celia Eliott (Minneapolis) - Specialist of Education From 2000 every year - Ardith Money (Iowa State University) - Professor of Political science and Director of International Programs in Iowa State University (Others) 2006, September - SENCER-Georgian-Armenian-American Congress (funded by SENCER Program and Sigma-Xi)- Organizer Educational activities: Teaching in different universities: Cytology: 1990 - 1992 Georgian Medical University Biochemistry and Chemistry:1990 - 1992 - Georgian Medical Academy Biology: 1999- today Tbilisi I. Chavchavadze University (Private) Systematically collaborates with colleges (neuroscientists) from Harrisburg, Iowa, Wayne State, Brown Universities USA), Univeristy of Helsinki, Institute of Molecular Biology (University of Kuopio, Finland).- Supervisor of 6 PhD students. Students and young PhDs work on probation in the universities of Finland, America, Germany.- Participates in preparation of joint project with neuroscientists from Wayne State University and Iowa State University. Membership of scientific societies: Sigma Xi ? American Scientific Research Society. Full member Sigma Xi-Georgia - President IBRO (International Brain Research Organization) European Society for NeuroscienceInternational Society for Neuroanatomists. Board member Russian Society for Electron MicroscopistsGeorgian Society of Physiologists Women in Neuroscience (Chapter of Society for Neuroscience) Fellowship of IWISE (International Woman in Science and Engineering)
Participation in Grant Projects
Languages
Georgian, Russian, English, French - fluent
Scientific interests
Structural and Molecular changes provoked by epilepsy, drug abuse, stress, hypokinesia and social isolation
Current scientific activities
Investigation of changes provoked on cellular level by epilepsy, and different drugs (alcohlol, toluol)
Future work plans
To continue current scientific activites, by using most modern methods; To implement some modern methods of neuroscience in the lab
Department
Computational Sciences