| Full Name |
Solomonia Revaz |
| Address |
Institute of Physiology, 14, L. Gotua Str., Tbilisi 0161, Georgia | | Phone |
+995 32 37 11 67 | | Fax |
+995 32 94 10 45 |
| E-mail |
|
| Web Page |
| | Date Of Birth |
1956-05-28 | | Education |
PROFESSIONAL EDUCATION AND ACADEMIC DEGREES
1973-1978 -Tbilisi State University, Faculty of Biology, Department of Biochemistry
1978 ………………………. Diplomed Biologist, Tbilisi State University, Chavchavadze Ave. 1, Tbilisi, Republic of Georgia
1978-1982 Post-graduate student at the Institute of Molecular Biology, Moscow
1983……………………….. Candidate of Biological Sciences (Ph.D), “ Purification and Characterisation of cyclic-nucleotide independent protein kinase from the myxomycete Physarum Polycephalum” Moscow State University, USSR
1992………………………. Doctor of Biological Sciences (Science Doctor)“Neuroreception and glycosylation reactions after visual imprinting in chicks” Institute of Physiology, Tbilisi (USSR)
| | Position |
Head of Laboratory of Biochemical Neuropharmacology, Institute of Physiology | | Publications |
Selected Publications
1. Maderspach, K. & Solomonia, R.O. (1988) Glial and neuronal opioid receptors: apparent positive cooperativity observed in intact cultured cells. Brain Research , 441. 41-47.
2. Van der Zee E.A., Bolhuis J.J., Solomonia R.O. , Horn G., and Luiten P.G.M. (1995) Differential distribution of protein kinase C (PKC alpha-beta and PKC gamma) isoenzyme immunoreactivity in the chick brain. Brain Research, 676, 41-52
3.Solomonia R.O., McCabe B.J., Jackson A.P., and Horn G. (1997) Clathrin Proteins and Recognition Memory. Neuroscience, 80, 59-67
4. Solomonia R.O., McCabe B.J. and Horn G. (1998) Neural Cell Adhesion Molecules, learning and Memory in the domestic chicks. Behavioural Neurosciences, 112, 646-655
5. Harvey R.J., McCabe B.J., Solomonia R.O., Horn G. and Darlison M.G. (1998) Expressiom of the GABAA receptor g4-subunit gene: anatomical distribution of the corresponding mRNA in the domestic chick forebrain and the effect of imprinting training. Eur. Journal of Neuroscience, 10, 3024-3028
6.Solomonia R.O., Kiguradze T. McCabe B.J. and Horn G. (2000) Neural cell adhesion molecules, calcium/calmodulin-dependent protein kinase II and long- term memory in domestic chicks. Neuroreport, 14, 11, 31139-3143
7. Mikeladze, E., Schulte, A., Mosbach, A., Blochl, E., Csoregi, E., Solomonia, R.& Schuhmann, W. (2002) Redox hydrogel-based bienzyme microelectrode for amperometric monitoring of L-glutamate. Electroanalysis, 14, 393-399.
8. Solomonia R. Morgan K., Kotorashvili A., McCabe B.J., Jackson A.P. & Horn G. (2003) Analysis of differential gene expression supports a role for amyloid precursor protein and a protein kinase C substrate (MARKCS) in long-term memory. Eur. J. Neurosci. 17, 1073-1081
9. Bolokadze N., Lobjanidze, N., Momtselidze, N., Solomonia, R., Shakarishvili,R. & Mchedlishvili, G. (2004) Blood rheological properties and lipid peroxidation in cerebral and systematic circulation of neurocritical patients. Clinical Hemorheology and Microcirculation, 30,2 99-105
10. Bolokadze N., Varasahvili M., Salia N., Momtselidze N., Solomonia R., Mchedlishvili G. (2004) Lipid peroxidation in the erythrocytes under condition of their increased aggregation.Clin Hemorheol Microcirc. 30(3-4):453-455.
11. Solomonia, R., Kuchiashvili, N., Berulava, A., Pkhakadze, V., Trapaidze, N., Zhvania, M., Abesadze, I., Kojima H., & Dalakishvili N. (2004) Purification and identification of components of the Aquilegia vulgaris extract fraction exhibiting anti-epileptic activity. Journal of Biological Physics and Chemistry, v4, p.185-192.
12. Solomonia R., Kotorashvili A., , Kiguradze T., McCabe B.J., & Horn G (2005) Ca2+/calmodulin protein kinase II and memory: learning-related changes in a localized region of the domestic chick brain J Physiol., 569 643–653
| | Conferences,contacts,other scientific and educational activities |
Scientific Collaboration with Sub-Department of animal behaviour, Department of Zoology, University of Cambridge | | Participation in Grant Projects |
INTERNATIONAL GRANTS
*1994-1996. Wellcome Trust Travel Fellowship, Department of Zoology, Cambidge University (RN -0338892/2/93 and extension 038899)
*1997-1998. Wellcome Trust collaborative Research Initiative grant with the Department of Zoology, Cambridge University “Tyrosine kinase signalling pathways, neural cell adhesion molecules and long-term memory”(RN- 047694/Z/96)
*1997-2000. INTAS grant “ Fast-responding Microbiosensors for recognition
memory brain research” (RN-96-1432)
*1999. 6 month Wellcome Trust travel award at the Department of Biochemistry, Cambridge University “Gene expression and long-term memory (RN -056634/Z/99/Z)
*2001-2004. International Science and Technology Center (ISTC), “Isolation and characterisation of compounds with antipeileptic activity from Aquilegia Vulgaris – the plant widely used in oriental folk medicine” (RN G-420)
*2001-2003. The Royal Society joint project with Sub-department of Animal Behaviour, Cambridge University “ Ca2+/calmodulin dependent protein kinase II and recognition memory in chicks” (RN gt/FSU/JP)
*2001-2002. “Georgian Awarness and Training Network” project (proposal ICA2
2000-50004; contract ICA2-CT2001-50002) funded by European Comission
*2002-2005 INTAS grant “High-Resolution lateral imaging of Neurological Activity using novel sensitive microbiosensors ( RN 2001-2065)
* 2006-2008. The Royal Society joint project with Sub-department of Animal Behaviour, Cambridge University “Ca2+/calmodulin dependent protein kinase II signaling, learning and memory (RN 2005R4/-JP)
IV.-A. PARTICIPATION IN OTHER INTERNATIONAL GRANTS:
* 2002-2005, International Science and Technology Center (ISTC) “ Prevention of Amebiasis and creation of diagnostic test-systems fro E.histolytica strains isolated in Georgia” (RN G-617p), group leader from the Institute of Physiology
* 2005-2008. Defense Threat Reduction Agency and U.S. Civilian Research and Development Foundation “Ecology, Genetic Clustering and Virulence of Yersinia pestis Strains Isolated from Natural Foci of Plague in Georgia” (RN (GEB2-1953-TB-05), group leader from the Institute of Physiology
| | Languages |
Georgian, English, Russian | | Scientific interests |
- Study of molecular basis of memory formation;
- Study of molecular mechanisms of epileptogenesis and ways for its prevention | | Current scientific activities |
| | Future work plans |
- Study of molecular basis of memory formation;
- Study of molecular mechanisms of epileptogenesis and ways for its prevention | | Department |
Computational Sciences |