Full Name
Mchedlishvili Nani
Address
Digmis masivi, 5/23/45, Tbilisi, 0159, Georgia
Phone
520 926 (home), 528 317 (office)
Fax
E-mail
Web Page
Date Of Birth
1956-07-12
Education
Tbilisi Ivane Javakhishvili State University, Faculty of Chemistry
Position
Doctor of biological sciences Leading scientist of Laboratory of Biotechnology of the Durmishidze Institute of Biochemistry and Biotechnology
Publications
Pruidze G.N., Omiadze N.T., Mchedlishvili N.I. Characterization of Monophenol Monooxygenase from Tea Leaves. Appl. Biochem. Microbiol. 1997, 33, N1, pp. 45-56, Jincharadze M., Pruidze G., Omiadze N., Mchedlishvili N. Effect of Tea Leaf Peptides on the Monophenol Monooxygenase and Catechol Oxidase Activities. Bulletin of Georgian Academy of Sciences. 1998, V. 157, N3, pp. 300-301 Mchedlishvili N.I., Pruidze G.N., Omiadze N.T., Zukhbaya R.V. Soluble and Immobilized Phenol Oxidase of the Fungus Mycelia sterilia IBR 35219/2: a Comparative Study. Appl. Biochem. Microbiol. 2000, V.36, N 2, pp.138-142. Омиадзе Н. Т., Пруидзе Г. Н., Мчедлишвили Н. И., Гулуа Л.К.Внутриклеточная локализация и характеристика монофенолмонооксигеназы листьев чайного растения . Укр. биохим. журн. 2000, т.72, #3, с.38-43. Omiadze N., Bendeliani E., Pruidze G., Mchedlishvili N. Effect of Tea Leaf Phenolic Compounds on the Activity of Barley Malt Peroxidase. Bulletin of Georgian Academy of Sciences. 2002, V.166, N1, pp.115-116. Gulua L.K., Pruidze G.N., Mchedlishvili N.I , Omiadze N.T., Pruidze N.G. A Novel Catechol Reductase Catalitic Activity of Tea Leaf Phenol Oxidase. Journal of Biological Physics and Chemistry ( JBPC). 2002, V.2, N ѕ, pp. 89-94. Pruidze G.N., Mchedlishvili N.I , Omiadze N.T., Gulua L.K., Pruidze N. G. Multiple Forms of Phenol Oxidase from Kolkhida Tea Leaves (Camellia sinensis L.) and Mycelia sterilia IBR 35219/2 and Their Role in Tea Production. Food Research International. 2003, V.36, N.6, pp.587-595. Zamtaradze R., Mchedlishvili N., Omiadze N., Pruidze G. Isolation of Phenoloxidase from Green Husk of Walnut (Juglans regia) and Study of its Properties. Bulletin of Georgian Academy of Sciences. 2003, V. 167, N.3, pp. 519-520. Mchedlishvili N., Zamtaradze R., Sadunishvili T., Omiadze N., Gulua L. Effect of Different Inhibitors on Phenoloxidase Activity from Green Husk of Walnut (Juglans regia L.). Proc. Georgian Acad. Sci., Biol. Ser. B 2004. Vol.2, No. 1-2, pp. 16-19. Omiadze N, Parlar H., Leupold G., Mchedlishvili N., Gulua L., Akhvlediani K., Abutidze M, Sadunishvili T., Rodrнguez – Lуpez J. N, Kvesitadze G. Inhibition of apple phenoloxidase and peroxidase by natural phenolics of tea leaves. Advances in Food Sciences 2004, V.26, N 1, pp.26-31. Zamtaradze R., Mchedlishvili N., Omiadze N., Gulua L., Abutidze M., Kvesitadze G. Monophenolase and Diphenolase Activities of Phenoloxidase from Walnut (Juglans regia L.) Green Husk. Bulletin of Georgian Academy of Sciences. 2004,V. 169, # 1, pp. 144-146. Omiadze N., Pruidze N., Mchedlishvili N., Gulua L., Abutidze M., Daushvili L., Kvesitadze G. Inhibition of Tea Leaf Phenoloxidase by Sulfur Dioxide. Bulletin of Georgian Academy of Sciences. 2004, V. 169, # 1, pp. 154-156. Omiadze N., Mchedlishvili N., Gulua L., Pruidze N., Abutidze M. Study of Multiple Forms of Phenol Oxidase from Kolkhida Tea Leaves. Bulletin of Georgian Academy of Sciences. 2004, V.170, N1, pp.155-157. Alyabyev A., Gordon L., Loseva N., Rachimova G., Tribunskih V., Estrina R., Sadunishvili T., Gulua L., Mchedlishvili N., Rodrigues-Lopez J.N. The Effect of a Natural Inhibitor Isolated from the Tea Leaf on the Energy Processes in Model Systems. Thermochimica Acta. 2004. V.422. N1-2, pp.109-113. Mchedlishvili N., Omiadze N., Gulua L. Nishnianidze N., Rekhviashvili M., Pruidze N. Dynamics of Accumulation of Tea Pigments during Tea (Camellia sinensis L.) Leaf Processimg. Proc. Georgian Acad. Sci., Biol. Ser. B. 2004. Vol.2, No. 5-6, pp.1-4. Bajinyan S. A., Kvesitadze G. I., Malakyan M. H., Pogosyan A.S., Dallakyan A.M., Mchedlisvili N. I., Omiadze N., N.T., Gulua L. K. Radiomodifying and Cytogenetic Activity of Green Tea Extract. European Radiation Research 2004. The 33-rd Annual Meeting of the European Society for Radiation Biology, August 25-28, 2004, Budapest, Hungary, p.9. Mchedlisvili N., Omiadze N., Gulua L., Sadunishvili T., Zamtaradze R., Abutidze M., Bendeliani E., Kvesitadze G. Thermostabilities of Plant Phenol Oxidase and Peroxidase Determining the Technology of Their Use in the Food Industry. Appl. Biochem. Microbiol. 2005, V.41, N 2, pp.165-170. Gulua L., Omiadze N., Mchedlisvili N., Chachua L. Tsiklauri G., Rekhviashvili M., Torbini V. Natural Inhibitor of Phenol Oxidases and Peroxidases from Pomegranate Peel. Proc. Georgian Acad. Sci., Biol. Ser. B. 2005. Vol.3, No. 1, pp.6-10. Zaletok S., Gulua L., Orlovsky A., Gogol S., Omiadze N., Mchedlisvili N., Kavetsky R. Effect of Green Tea Extract on the Growth of Experimental Breast Tumours. International Research Conference on Food, Nutrition and Cancer. Poster Abstract Book. Washington, DC, July 14-15, 2005, p 71. Gulua L., Shalamberidze M., Khutsidze T., Omiadze N., Mchedlishvili N., Abutidze. Investigation of some biologically active compounds and antioxidant activity of green tea dry extract from Kolkhida tea leaves. Bulletin of Georgian Academy of Sciences. 2006, V.173, N1, p.151-153.
Conferences,contacts,other scientific and educational activities
International conference Natural Compounds and Regulators of metabolism and adaptation of plants, Almaty, Kazakhstan, 1999; The 33-rd Annual Meeting of the European Society for Radiation Biology, August 25-28, 2004, Budapest, Hungary; . International Research Conference on Food, Nutrition and Cancer. Poster Abstract Book. Washington, DC, July 14-15, 2005.
Participation in Grant Projects
Intenatiolal grants 2001- 2004 - Food, Ref. No : 2000-00727. Prevention of food spoilage by Sup­­pression of phenoloxidase, Peroxidase and Growth of Pathogenic Microflora by Use of Natural Inhibitors of Plant Origin. 2004-2006 -STCU GG-122 . Creating Plant Bioconcentrates with High Antiradiation and Anticarcinogenic Action on the Base of Polyphenols and Working out Industrial Technology for Their Production. ( http://www.intas.be/mainfs.htm) Grants of Academy of Sciences of Georgia 2000 – 2001 – #14.5. ; 2002 – 2003. – #14.5; 02. 2004 – 2005 – #14.4.04.
Languages
English and Russian
Scientific interests
Investigation of oxidase-reductase enzymes( phenoloxidase and peroxidase) Production of natural colours
Current scientific activities
Investigation of oxidase-reductase enzymes( phenoloxidase and peroxidase) Production of natural colours
Future work plans
Investigation of oxidase-reductase enzymes( phenoloxidase and peroxidase) Production of natural colours
Department
Computational Sciences